Punchline (1988) on Netflix

Steven Gold is a stand-up comedian who is flat broke and has recently dropped out of medical school. He and several others work regularly at the Gas Station, a New York comedy club. The wages are lousy and everybody hopes for the big break. Lilah Krytsick is housewife with an ambition to be a stand-up comedian, however she doesnt seem to have the talent. Steven takes her under his wings and teaches her the art of comedy and humour. But when a TV station arranges a comedy evening at the club, Steve sees his opportunity for fame and stardom. Their friendship seems quickly forgotten and now it's every man and woman for him- or herself!