Football player Bob Miller, played by an actual football player, is lost in the jungle. Who else to find him but Jungle Jim.
After Jungle Jim rescues Anne Lawrence from deadly rapids, he learns that she is looking for one-time football hero Bob Miller who disappeared 9 years before when his military flight disappeared over the jungle. There are problems in the area and tribes are being attacked and enslaved by the Skeleton Men. They learn that a white man with a gun is leading the Skeleton Men and Anne fears that it might be Miller. The tribesmen are being put into forced labor in a mine and Jim sets out to rescue them. Along the way they will meet strange creatures and eventually be taken prisoner themselves. Jim finds a way out.