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A group of medical students devise a deadly game: to see which one of them can commit the perfect murder.

Ted Grey is a brilliant medical student graduated from Harvard with a training period in Lagos, Africa, and a lovely fiancée, Gwen Williamson, from a wealthy and influential family. When he joins the Medical Center of the Metropolitan University in the department of Pathology and Forensics, he becomes the pride and joy of his professor Dr. Quentin Morris. However the star of the residence, Jake Gallo, becomes jealous with the newcomer. Nevertheless he invites Ted to participate with four other residents in a deadly game, where each participant must commit the perfect crime without any clue to reveal the "modus-operandi" of the murder, and the others investigate the corpse in the dungeon of the hospital. When Gwen decides to move to Ted's apartment, he decides to leave the group, but he finds resistance.


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