Snakeman (2005) on Netflix

Plot summary

The remains of a man recovered deep in the Amazon are determined to be approximately 300 years old. The discovery points toward the secret of eternal youth, and a second expedition is organized to find the fountain of youth. Dr. Susan Elters leads the scientists, Matt Ford serves as their guide, and local Amazonians travel with them. Their route runs through the jungle toward the territory of a tribe called the Snake People, a journey that costs the group part of its crew. The tribe guards the fountain of youth, and it also worships a giant snake with several heads.